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Microcrystalline Cellulose (MCC)

CAS Number: 9004-34-6

Microcrystalline cellulose (MCC, E460) is a purified, partially depolymerized cellulose derived from alpha-cellulose pulp, available as free-flowing powder (PH-101, PH-102) and gel-forming colloidal grades (RC/CL). In food applications, it serves as an anti-caking agent, fat replacer, texturizer, and dietary fiber source. Its non-digestibility (0 kcal/g) makes it valuable in calorie-reduced foods, and its compressibility makes it the most widely used direct-compression excipient in tablet manufacturing.

Technical Specifications

appearanceWhite to off-white fine powder or granules
moisture (%)≤5.0
pH (2% slurry)5.0–7.5
heavy metals (ppm)≤10
degree of polymerization (DP)~220–260 (PH-101)

Applications

  • Food powder and dry mix anti-caking agent
  • Low-calorie salad dressings and mayonnaise fat replacer
  • Grated cheese anti-sticking and free-flow agent
  • Dietary supplement tablet direct compression binder
  • Beverage and dairy product texturizer (colloidal MCC)

Key Features

  • Excellent direct compression properties for tablet manufacturing (USP NF grade)
  • Zero caloric value as dietary fiber for calorie-reduced product claims
  • Colloidal grade (RC) provides superior suspension and fat-replacement function
  • EU E460 approved, GRAS status, USP/NF and FCC grade available

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Microcrystalline Cellulose (MCC) chemical structure

CAS Number

9004-34-6

Availability

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