Nisin
CAS Number: 1414-45-5
Nisin is a natural antimicrobial peptide produced by Lactococcus lactis, classified as a bacteriocin. It exhibits potent activity against a broad range of Gram-positive bacteria and bacterial spores, including Listeria, Bacillus, and Clostridium species. Commonly available as a standardized preparation (2.5% nisin activity, diluted with NaCl and defatted milk powder) and approved globally as E234.
Technical Specifications
| appearance | Off-white to light tan powder |
| moisture (%) | ≤3.0 |
| pH (1% solution) | 3.5–5.0 |
| heavy metals (ppm) | ≤10 |
| nisin activity (IU/mg) | ≥1000 |
Applications
- Processed cheese and dairy product preservation
- Ready-to-eat meat and poultry products
- Pasteurized liquid egg and egg products
- Canned and retorted foods as a heat-process adjunct
- Fermented beverages and breweries
Key Features
- 100% natural origin, produced by fermentation of L. lactis
- GRAS status (FDA), approved EU E234, Codex Alimentarius listed
- Active against heat-resistant Bacillus and Clostridium spores
- No cross-resistance with clinical antibiotics reported
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CAS Number
1414-45-5
Category
Food / Beverage AdditivesAvailability
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