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Ergothioneine

CAS Number: 497-30-3

Ergothioneine is a naturally occurring histidine-derived thiol amino acid produced by fungi and actinobacteria, recognized as a 'longevity vitamin' due to its exceptional antioxidant potency surpassing glutathione, vitamins C and E combined, and its ability to accumulate in tissues under oxidative stress. It protects mitochondrial DNA and proteins from oxidative damage and is emerging as a premier anti-aging ingredient. Used at 0.005–0.1% in high-performance anti-aging formulations.

Technical Specifications

appearanceWhite to off-white crystalline powder
purity (%)≥98
pH (1% aq.)7.0–9.0
moisture (%)≤1.0
heavy metals (ppm)≤10

Applications

  • Premium anti-aging antioxidant serums
  • Mitochondria-protective skincare formulations
  • Environmental and blue light protection products
  • Longevity-focused skin health treatments
  • Synergistic antioxidant complex formulations

Key Features

  • Antioxidant potency exceeding glutathione and vitamins C+E combined
  • Accumulates in high-stress tissues providing targeted cellular protection
  • Protects mitochondrial DNA and lipids from oxidative damage
  • Highly stable in formulations, maintaining activity over shelf life

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Ergothioneine chemical structure

CAS Number

497-30-3

Availability

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