Hydroxypinacolone Retinoate (HPR)
CAS Number: 893412-73-2
Hydroxypinacolone Retinoate (HPR) is a next-generation retinoic acid ester that binds directly to retinoid receptors in the skin without requiring enzymatic conversion, delivering retinoic acid-like efficacy with dramatically reduced irritation and photosensitivity. It is considered one of the gentlest yet most effective retinoids available for cosmetic use. Ideal for sensitive skin formulations at 0.01–0.1%.
Technical Specifications
| acid value | ≤1.0 mg KOH/g |
| appearance | Light yellow to yellow oily liquid or soft solid |
| purity (%) | ≥95 |
| moisture (%) | ≤0.3 |
| refractive index | 1.510–1.530 |
Applications
- Sensitive skin anti-aging formulations
- Daily-use retinoid products
- Combination retinoid serums
- Eye area treatments
- Pregnancy-safe alternative retinoid products
Key Features
- Direct retinoic acid receptor binding without enzymatic conversion
- Significantly lower irritation than retinol or retinaldehyde
- Stable to light and oxidation compared to other retinoids
- Suitable for daily use and sensitive or reactive skin types
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CAS Number
893412-73-2
Category
Cosmetic Active IngredientsAvailability
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