Citric Acid (Pharmaceutical Grade)
CAS Number: 77-92-9
Pharmaceutical grade Citric Acid is a tricarboxylic acid used as a pH adjuster, buffering agent, chelating agent, and acidulant in a wide range of oral, parenteral, and topical formulations. Its ability to chelate divalent metal ions makes it particularly effective as a metal-sequestering antioxidant synergist. It is also an essential component of effervescent tablet formulations.
Technical Specifications
| appearance | White crystalline powder or granules |
| sulfate (ppm) | ≤150 |
| pH (1% solution) | ~2.2 |
| heavy metals (ppm) | ≤10 |
| loss on drying (%) | ≤0.5 |
| assay (anhydrous basis, %) | 99.5–100.5 |
Applications
- pH adjuster in liquid formulations
- Buffer system component
- Chelating agent / antioxidant synergist
- Effervescent tablet acid component
- Taste modifier and flavoring
Key Features
- Effective pH adjustment and buffering
- Metal chelation enhances antioxidant protection
- Key component for effervescent systems
- USP/NF, EP, JP, ChP compliant
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CAS Number
77-92-9
Category
Pharmaceutical ExcipientsAvailability
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