Cellulose Acetate Phthalate (CAP)
CAS Number: 9004-38-0
Cellulose Acetate Phthalate (CAP) is a widely used enteric coating polymer that remains intact in gastric acid but dissolves above pH 6.0 in the intestine. It provides effective protection of acid-sensitive APIs from gastric degradation and enables targeted drug delivery to the small intestine. It can be applied from organic solvent solutions or aqueous dispersions.
Technical Specifications
| appearance | White to off-white free-flowing powder |
| viscosity (cP) | 45–90 |
| pH of dissolution | ≥6.0 |
| acetyl content (%) | 17.0–26.0 |
| loss on drying (%) | ≤5.0 |
| phthalyl content (%) | 30.0–36.0 |
Applications
- Enteric tablet and capsule coating
- Acid-sensitive API protection
- Intestinal targeted drug delivery
- Pellet enteric coating
- Sustained-release systems
Key Features
- Effective enteric protection at pH ≥6.0
- Soluble in organic solvents and aqueous systems
- Long history of safe use
- USP/NF, EP compliant
Send Inquiry
CAS Number
9004-38-0
Category
Pharmaceutical ExcipientsAvailability
In StockSample
Dispatched within 5 days
More in Pharmaceutical Excipients
Ascorbic Acid (Vitamin C, Pharmaceutical Grade)
50-81-7
Benzyl Alcohol (Pharmaceutical Grade Preservative)
100-51-6
Calcium Stearate (Pharmaceutical Grade)
1592-23-0
Carnauba Wax (Pharmaceutical Grade)
8015-86-9
Citric Acid (Pharmaceutical Grade)
77-92-9
Colloidal Silicon Dioxide (Aerosil 200)
7631-86-9
Copovidone VA64 (Kollidon VA64)
25086-89-9
Corn Starch (Pharmaceutical Grade)
9005-25-8