Eudragit L100 (Methacrylic Acid Copolymer Type A)
CAS Number: 25212-88-8
Eudragit L100 is an anionic copolymer of methacrylic acid and methyl methacrylate used as an enteric coating polymer, dissolving at pH 6.0 and above. It provides reliable protection against gastric acid and enables targeted drug release in the duodenum and jejunum. It is applied from organic solvent or aqueous dispersion coating systems.
Technical Specifications
| appearance | White powder with faint amine odor |
| pH of dissolution | ≥6.0 |
| loss on drying (%) | ≤5.0 |
| acid value (mg KOH/g) | 300–330 |
| residual monomer (ppm) | ≤100 |
Applications
- Enteric tablet and capsule coating
- Intestinal targeted drug release
- Acid-sensitive API protection
- Pellet enteric coating
- Nutraceutical delayed-release formulations
Key Features
- Targeted dissolution at pH ≥6.0
- Robust gastric resistance
- Multiple processing options (solvent, aqueous)
- Ph.Eur., USP/NF compliant
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CAS Number
25212-88-8
Category
Pharmaceutical ExcipientsAvailability
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