Polyvinyl Acetate Phthalate (PVAP)
CAS Number: 50865-01-5
Polyvinyl Acetate Phthalate (PVAP) is an enteric coating polymer that remains stable in acidic gastric conditions but dissolves rapidly at pH 5.0 and above, making it suitable for early intestinal drug release. It can be applied as an organic solvent solution or aqueous dispersion and exhibits excellent resistance to moisture uptake during storage.
Technical Specifications
| appearance | White to slightly off-white powder |
| pH of dissolution | ≥5.0 |
| loss on drying (%) | ≤3.0 |
| phthalyl content (%) | 55.0–62.0 |
| viscosity 15% in acetone/water (mPa·s) | 7–14 |
Applications
- Enteric coating for tablets and pellets
- Moisture-sensitive API protection
- Early intestinal drug release
- Aqueous enteric coating systems
- Nutraceutical enteric coating
Key Features
- Dissolves at pH ≥5.0 for early intestinal release
- Low moisture uptake during storage
- Aqueous and organic solvent compatible
- USP/NF compliant
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CAS Number
50865-01-5
Category
Pharmaceutical ExcipientsAvailability
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