Hydrolyzed Hyaluronic Acid (Low MW HA)
CAS Number: 9004-61-9
Hydrolyzed Hyaluronic Acid consists of low-molecular-weight hyaluronic acid fragments (typically 5–50 kDa or smaller) produced by enzymatic or chemical hydrolysis of high-molecular-weight HA, enabling deeper skin penetration to the viable epidermis and upper dermis where they provide hydration, stimulate HA synthesis, and offer anti-inflammatory benefits. Unlike standard HMW HA that sits on the skin surface, hydrolyzed HA acts at multiple skin layers. Used at 0.01–1% in deep-hydrating formulations.
Technical Specifications
| appearance | White to off-white powder |
| moisture (%) | ≤8.0 |
| HA content (%) | ≥90 |
| molecular weight | 5,000–50,000 Da |
| heavy metals (ppm) | ≤10 |
Applications
- Deep penetrating hydration serums
- Multi-molecular-weight HA layering formulations
- Anti-aging dermis-targeting moisturizers
- Under-eye and fine line hydrating treatments
- Combination HA complex skin hydration products
Key Features
- Low MW enables transepidermal penetration to dermis for deep hydration
- Stimulates endogenous HA synthesis in dermal fibroblasts
- Provides anti-inflammatory benefits beyond surface moisturization
- Complements standard HMW HA in multi-weight HA serum systems
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CAS Number
9004-61-9
Category
Cosmetic Active IngredientsAvailability
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