anti aging cosmetic actives

Fermented Yeast Extract

CAS: 8013-01-2

Fermented Yeast Extract is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Ferulic Acid (Cosmetic Grade)

CAS: 1135-24-6

Ferulic acid is a potent plant-derived hydroxycinnamic acid antioxidant that not only neutralizes free radicals independently but also dramatically enhances the stability and efficacy of vitamins C and E, making it a cornerstone ingredient in antioxidant serums. It protects skin against UV-induced oxidative damage and has mild brightening and anti-aging properties. Used at 0.5–1% in vitamin C antioxidant serums.

anti aging cosmetic actives

Galactomyces Ferment Filtrate

CAS: 68648-45-3

Galactomyces Ferment Filtrate is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Glutathione (Cosmetic Grade)

CAS: 70-18-8

Glutathione is the body's master antioxidant tripeptide (gamma-glutamyl-cysteinyl-glycine), naturally present in all cells, that exerts potent skin brightening effects by switching melanin biosynthesis from dark eumelanin to lighter phaeomelanin, while also protecting skin from oxidative damage. It is particularly popular in Asian and global brightening skincare for its safe, effective, and multi-mechanistic whitening activity. Used at 0.1–2% in brightening serums and creams.

anti aging cosmetic actives

Hydroxyproline Cosmetic

CAS: 51-35-4

Hydroxyproline Cosmetic is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Idebenone Cosmetic

CAS: 58186-27-9

Idebenone Cosmetic is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Kojic Acid Cosmetic

CAS: 501-30-4

Kojic Acid Cosmetic is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Leuphasyl Peptide

CAS: 959610-30-1

Leuphasyl Peptide is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Madecassoside Cosmetic

CAS: 34540-22-2

Madecassoside Cosmetic is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Matrixyl Palmitoyl Pentapeptide

CAS: 214047-00-4

Matrixyl Palmitoyl Pentapeptide is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Niacinamide (Vitamin B3) Cosmetic Grade

CAS: 98-92-0

Niacinamide (Vitamin B3) Cosmetic Grade is the most widely used skin-brightening active in modern formulation, clinically proven to inhibit melanosome transfer from melanocytes to keratinocytes, visibly reducing dark spots and uneven tone. It simultaneously reduces sebum production, strengthens the epidermal barrier by stimulating ceramide and fatty acid synthesis, and minimizes pore appearance. Water-soluble and heat-stable, it is compatible with the majority of cosmetic actives at 2–10% use levels.

anti aging cosmetic actives

Palmitoyl Tetrapeptide-7 (GQPR Peptide)

CAS: 221227-05-0

Palmitoyl Tetrapeptide-7 is a lipopeptide consisting of a palmitoyl fatty acid chain conjugated to the tetrapeptide Gly-Gln-Pro-Arg (GQPR), which is a fragment of immunoglobulin G. It acts by inhibiting interleukin-6 (IL-6) signaling to suppress chronic low-grade skin inflammation (inflammaging), reduce glycation-induced cross-linking, and improve skin density. As the partner peptide to Palmitoyl Tripeptide-1 in the commercially recognized Matrixyl 3000 complex, it delivers synergistic anti-wrinkle efficacy at just 2–4 ppm use level.

anti aging cosmetic actives

Palmitoyl Tripeptide

CAS: 685898-44-6

Palmitoyl Tripeptide is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Phytosphingosine (t-C18 Sphingoid Base)

CAS: 554-62-1

Phytosphingosine is a natural sphingoid base (t-C18) produced by yeast fermentation, functioning as a direct precursor to ceramide biosynthesis in the skin and a potent antimicrobial agent against acne-causing bacteria (Cutibacterium acnes) and Pityrosporum ovale. By stimulating ceramide synthesis it reinforces the lamellar lipid structure of the stratum corneum, restoring barrier function in compromised skin. Used at 0.05–0.1% in anti-acne, ceramide-booster, and sensitive skin formulations.

anti aging cosmetic actives

Resveratrol Cosmetic

CAS: 501-36-0

Resveratrol Cosmetic is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Retinol Vitamin A Cosmetic

CAS: 68-26-8

Retinol Vitamin A Cosmetic is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Retinyl Palmitate (Vitamin A Palmitate)

CAS: 79-81-2

Retinyl Palmitate is an ester of retinol and palmitic acid, representing the mildest and most stable form in the retinoid family. Upon skin absorption it undergoes stepwise enzymatic conversion: retinyl palmitate → retinol → retinaldehyde → retinoic acid, progressively stimulating collagen synthesis, accelerating cell turnover, and reducing fine lines. Its oil-soluble, low-irritation profile makes it suitable for sensitive skin, eye serums, and daily-use night creams at 0.1–2%.

anti aging cosmetic actives

Sea Kelp Bioferment (Macrocystis Pyrifera)

Sea Kelp Bioferment is produced by fermenting giant kelp (Macrocystis pyrifera) with beneficial microorganisms, yielding a nutrient-dense liquid concentrate rich in bioavailable amino acids, polysaccharides (alginate, fucoidan, mannose, galactose), vitamins, and trace minerals. The fermentation process breaks down the kelp cell wall for enhanced bioavailability and creates postbiotic metabolites that balance the skin microbiome and strengthen the epidermal barrier. Used at 1–5% in face serums, scalp treatments, and microbiome-focused skincare.

anti aging cosmetic actives

Sodium Ascorbyl Phosphate

CAS: 66170-10-3

Sodium Ascorbyl Phosphate is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Sodium Hyaluronate (Hyaluronic Acid) Cosmetic Grade

CAS: 9067-32-7

Sodium Hyaluronate Cosmetic Grade is the gold-standard humectant in skincare, capable of holding up to 1000 times its own weight in water to deliver immediate plumping and long-lasting hydration. Available in high molecular weight (1–1.8 MDa, forms a surface moisture-retention film) and low molecular weight (5–200 kDa, penetrates deeper for structural hydration), enabling layered hydration strategies. Used at 0.01–2% across toners, serums, sheet masks, and moisturizers.

anti aging cosmetic actives

Squalane Cosmetic

CAS: 111-01-3

Squalane Cosmetic is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Syn-Ake Peptide

CAS: Syn-Ake

Syn-Ake Peptide is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.

anti aging cosmetic actives

Tranexamic Acid (Cosmetic Grade)

CAS: 1197-18-8

Tranexamic acid is a synthetic lysine derivative that inhibits melanin synthesis by blocking the interaction between keratinocytes and melanocytes, effectively reducing hyperpigmentation, dark spots, and uneven skin tone with excellent safety and tolerability. It works through a different pathway than traditional brightening agents, making it ideal for combination brightening formulas. Used at 2–5% in serums, toners, and brightening creams.

anti aging cosmetic actives

Transforming Growth Factor TGF

CAS: 90820-95-4

Transforming Growth Factor TGF is a clinically-validated cosmetic active ingredient for anti-aging skincare formulations. Targets wrinkles, skin elasticity, and luminosity with proven efficacy.