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Ascorbic Acid (Vitamin C, Pharmaceutical Grade)

CAS Number: 50-81-7

Pharmaceutical grade Ascorbic Acid (Vitamin C) is used as an antioxidant stabilizer in oral, parenteral, and topical formulations to prevent oxidative degradation of susceptible APIs and excipients. It scavenges free radicals and reduces dissolved oxygen, protecting formulations during manufacturing and storage. It also finds use as a pH adjuster and as an active ingredient in nutraceutical and vitamin C supplement products.

Technical Specifications

assay (%)99.0–100.5
appearanceWhite or almost white crystalline powder
pH (5% solution)2.2–2.5
heavy metals (ppm)≤20
loss on drying (%)≤0.4
specific rotation (°)+20.5 to +21.5

Applications

  • Antioxidant stabilizer in oral formulations
  • Parenteral antioxidant
  • pH adjustment in liquid formulations
  • Nutraceutical and vitamin supplement
  • Topical antioxidant in cosmetics

Key Features

  • Potent water-soluble antioxidant
  • Effective at very low concentrations
  • Dual role as excipient and active ingredient
  • USP/NF, EP, JP, ChP compliant

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Ascorbic Acid (Vitamin C, Pharmaceutical Grade) chemical structure

CAS Number

50-81-7

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