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Mannitol (Pharmaceutical Grade)

CAS Number: 69-65-8

Pharmaceutical grade Mannitol is a sugar alcohol excipient used extensively as a diluent and bulking agent in tablet, lyophilized, and parenteral formulations. Its low hygroscopicity, pleasant taste, and cooling sensation make it ideal for chewable and orally disintegrating tablets. Compliant with USP/NF, EP, JP, and ChP standards.

Technical Specifications

assay (%)≥99.0
appearanceWhite crystalline powder
pH (5% solution)4.5–7.0
heavy metals (ppm)≤5
loss on drying (%)≤0.3
reducing sugars (%)≤0.2

Applications

  • Chewable and orally disintegrating tablets
  • Lyophilization bulking agent
  • Parenteral diluent
  • Direct compression filler
  • Confectionery and nutraceutical applications

Key Features

  • Low hygroscopicity for stable formulations
  • Pleasant sweet taste with cooling effect
  • Suitable for lyophilization and injectables
  • USP/NF, EP, JP, ChP compliant

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Mannitol (Pharmaceutical Grade) chemical structure

CAS Number

69-65-8

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