1,4-Dioxane
CAS Number: 123-91-1
1,4-Dioxane (≥99.5%) is a cyclic diether solvent with very high polarity, complete water miscibility, and exceptional solvency for cellulose, resins, and inorganic salts. It is used as a reaction solvent for challenging chemical synthesis, a carrier for pharmaceutical formulations, a wetting agent for analytical solutions, and a stabilizer for 1,1,1-trichloroethane.
Technical Specifications
| appearance | Colorless clear liquid |
| purity (%) | ≥99.5 |
| water content (%) | ≤0.05 |
| boiling point (°C) | 101.1 |
| density (g/mL, 20°C) | 1.033–1.036 |
| peroxide content (ppm) | ≤5 |
Applications
- Reaction solvent for challenging organic synthesis requiring high polarity
- Scintillation cocktail preparation in radioactivity analysis
- Pharmaceutical intermediate synthesis and purification solvent
- Wetting and dispersing agent in analytical and diagnostic reagents
- Surfactant synthesis as ethylene oxide adduct (as an impurity/stabilizer)
Key Features
- High purity ≥99.5% with controlled peroxide levels ensuring safe laboratory and industrial use
- Complete water miscibility enabling use as a bridge solvent between aqueous and organic systems
- High polarity and inertness making it a reliable non-nucleophilic reaction solvent
- Consistent quality with certificate of analysis including peroxide and water content documentation
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CAS Number
123-91-1
Category
Industrial Solvents / ChemicalsAvailability
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