Glycerin (Pharmaceutical Grade)
CAS Number: 56-81-5
Pharmaceutical grade Glycerin (glycerol) is a trihydric alcohol used extensively as a humectant, solvent, sweetener, and plasticizer in oral, topical, parenteral, and ophthalmic formulations. Its hygroscopic nature, high water miscibility, and low toxicity make it a versatile excipient for liquid and semisolid preparations. It is also used as a suppository base and as a lubricant in capsule fill operations.
Technical Specifications
| assay (%) | ≥99.5 |
| appearance | Clear, colorless, viscous liquid |
| water content (%) | ≤0.5 |
| heavy metals (ppm) | ≤5 |
| diethylene glycol (%) | ≤0.1 |
| specific gravity (25°C) | 1.257–1.262 |
Applications
- Humectant in topical and oral formulations
- Solvent for APIs and excipients
- Suppository base component
- Ophthalmic lubricant
- Plasticizer in film coatings
Key Features
- Highly miscible with water and alcohols
- Low toxicity for multiple routes
- Excellent humectant and solvent
- USP/NF, EP, JP, ChP compliant
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CAS Number
56-81-5
Category
Pharmaceutical ExcipientsAvailability
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