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Hydroxypropyl Cellulose LF (HPC LF)

CAS Number: 9004-64-2

Hydroxypropyl Cellulose LF is a low-viscosity grade of HPC with a 2% aqueous viscosity of approximately 75–150 mPa·s, primarily used as a binder in tablet and granule formulations. It dissolves in both water and organic solvents and exhibits thermoplastic properties, making it suitable for hot melt extrusion processes in addition to conventional manufacturing.

Technical Specifications

appearanceWhite to slightly yellowish powder
pH (1% solution)5.0–8.5
heavy metals (ppm)≤10
loss on drying (%)≤5.0
viscosity 2% aq. (mPa·s)75–150
hydroxypropoxy content (%)53.4–77.5

Applications

  • Wet granulation binder
  • Hot melt extrusion binder
  • Film coating polymer
  • Immediate release tablet binder
  • Extrusion-spheronization aid

Key Features

  • Thermoplastic for hot melt extrusion
  • Soluble in water and organic solvents
  • Excellent granule strength
  • USP/NF, EP, JP compliant

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Hydroxypropyl Cellulose LF (HPC LF) chemical structure

CAS Number

9004-64-2

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