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Propylparaben (Pharmaceutical Grade)

CAS Number: 94-13-3

Pharmaceutical grade Propylparaben (propyl 4-hydroxybenzoate) is an antimicrobial preservative used in combination with methylparaben to provide synergistic broad-spectrum antimicrobial protection in oral, topical, and parenteral formulations. Its higher lipophilicity compared to methylparaben makes it effective against fungi and lipophilic organisms. It is effective at low concentrations (0.01–0.1%).

Technical Specifications

assay (%)99.0–101.0
appearanceWhite crystalline powder
sulfated ash (%)≤0.1
heavy metals (ppm)≤10
loss on drying (%)≤0.5
melting range (°C)96–99

Applications

  • Combination preservative with methylparaben
  • Oral liquid and suspension preservative
  • Topical formulation antifungal preservative
  • Parenteral multi-dose preservative
  • Cosmetic preservation

Key Features

  • Higher lipophilicity for antifungal activity
  • Synergistic with methylparaben
  • Effective at very low concentrations
  • USP/NF, EP compliant

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Propylparaben (Pharmaceutical Grade) chemical structure

CAS Number

94-13-3

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