Sodium Starch Glycolate (Explotab)
CAS Number: 9063-38-1
Sodium Starch Glycolate is a sodium salt of carboxymethyl ether of starch, used as a superdisintegrant in tablet and capsule formulations. It absorbs water rapidly, causing significant swelling that disrupts tablet structure and enables rapid drug release. It is effective at low levels (2–8%) and is compatible with water-soluble and water-insoluble APIs.
Technical Specifications
| appearance | White to off-white free-flowing powder |
| heavy metals (ppm) | ≤20 |
| loss on drying (%) | ≤10.0 |
| sodium content (%) | 2.8–4.2 |
| pH (3.3% suspension) | 5.5–7.5 |
Applications
- Tablet and capsule superdisintegrant
- Immediate release solid dosage forms
- Wet and dry granulation
- Direct compression formulations
- Orally disintegrating tablets
Key Features
- Rapid water absorption and swelling
- Effective at 2–8% concentration
- Three grades available (Type A, B, C)
- USP/NF, EP, JP compliant
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CAS Number
9063-38-1
Category
Pharmaceutical ExcipientsAvailability
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