Chlorhexidine Gluconate (CHG)
CAS Number: 18472-51-0
Chlorhexidine gluconate (CHG) is a cationic bisbiguanide antiseptic with exceptional broad-spectrum activity against bacteria and fungi. It provides a persistent antimicrobial residual effect on skin due to its binding to keratin proteins, making it the gold standard in surgical hand antisepsis, wound care, and preoperative skin preparation. Available as a 20% concentrate solution.
Technical Specifications
| appearance | Clear colorless to pale yellow solution |
| pH (as is) | 5.5–7.0 |
| CHG content (%) | 19.0–21.0 |
| heavy metals as Pb (ppm) | ≤10 |
| related substances (HPLC) | per pharmacopeia |
Applications
- Surgical hand scrub and rub formulations
- Preoperative patient skin preparation
- Wound antiseptic cleansers and gels
- Oral antiseptic mouthwash
- Catheter and medical device antisepsis
Key Features
- Persistent residual antimicrobial effect on skin
- Broad-spectrum efficacy against bacteria and fungi
- Long history of clinical use and safety record
- Compatible with alcohol for enhanced rapid-kill formulas
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CAS Number
18472-51-0
Category
Cleaning / Hygiene ChemicalsAvailability
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