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Polyethylene Glycol 6000 (PEG 6000, Pharmaceutical Grade)

CAS Number: 25322-68-3

Pharmaceutical grade PEG 6000 is a higher-molecular-weight solid polyethylene glycol with an average MW of 5500–7500 Da, offering increased viscosity and a higher melting point compared to PEG 4000. It is used as a suppository base, tablet binder, film coating plasticizer, and melt granulation carrier. Its water solubility and biocompatibility make it suitable for diverse oral and rectal formulations.

Technical Specifications

appearanceWhite waxy solid or flakes
average MW (Da)5500–7500
pH (5% solution)4.5–7.5
loss on drying (%)≤0.5
melting point (°C)56–63
hydroxyl value (mg KOH/g)15–22

Applications

  • Suppository base
  • Tablet binder and plasticizer
  • Film coating agent
  • Melt granulation carrier
  • Controlled release matrix component

Key Features

  • Higher MW for improved viscosity control
  • Ideal suppository and coating base
  • Water-soluble and biocompatible
  • USP/NF, EP compliant

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Polyethylene Glycol 6000 (PEG 6000, Pharmaceutical Grade) chemical structure

CAS Number

25322-68-3

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