Polysorbate 80 (Tween 80, Pharmaceutical Grade)
CAS Number: 9005-65-6
Pharmaceutical grade Polysorbate 80 (Tween 80) is a widely used nonionic surfactant and emulsifier for oral, parenteral, and topical dosage forms. It effectively solubilizes and wets hydrophobic APIs and is used to stabilize emulsions, microemulsions, and nanosuspensions. It is also employed in biopharmaceutical formulations to prevent protein aggregation.
Technical Specifications
| HLB value | ~15 |
| appearance | Amber to yellow viscous liquid |
| water content (%) | ≤3.0 |
| acid value (mg KOH/g) | ≤2.0 |
| viscosity at 25°C (mPa·s) | 300–500 |
| saponification value (mg KOH/g) | 45–55 |
Applications
- Solubilizer for poorly water-soluble APIs
- Emulsifier for oral and parenteral emulsions
- Stabilizer for protein biopharmaceuticals
- Wetting agent in tablet coating
- Nanosuspension stabilizer
Key Features
- High HLB nonionic surfactant
- Broad spectrum solubilization
- Compatible with parenteral use
- USP/NF, EP compliant
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CAS Number
9005-65-6
Category
Pharmaceutical ExcipientsAvailability
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