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Propylene Glycol (Pharmaceutical Grade)

CAS Number: 57-55-6

Pharmaceutical grade Propylene Glycol (1,2-propanediol) is a versatile, generally recognized as safe (GRAS) solvent and humectant used in oral, parenteral, topical, and inhalation formulations. It effectively dissolves a wide range of poorly water-soluble APIs, acts as a plasticizer for film coatings, and serves as a preservative co-solvent in liquid formulations.

Technical Specifications

assay (%)≥99.5
appearanceClear, colorless, viscous liquid
water content (%)≤0.2
heavy metals (ppm)≤5
specific gravity (25°C)1.035–1.040
viscosity at 25°C (mPa·s)~40–60

Applications

  • Solvent for poorly water-soluble APIs
  • Film coating plasticizer
  • Topical formulation humectant
  • Parenteral co-solvent
  • Oral liquid vehicle

Key Features

  • GRAS status for multiple routes of administration
  • Excellent solvency for hydrophobic APIs
  • Effective plasticizer and humectant
  • USP/NF, EP compliant

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Propylene Glycol (Pharmaceutical Grade) chemical structure

CAS Number

57-55-6

Availability

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