Pharmaceutical Excipients
50 products
Pharmaceutical Excipients
Binders, fillers, disintegrants & coating polymers for drug formulation
50 products
50 products
pharmaceutical excipients
Ascorbic Acid (Vitamin C, Pharmaceutical Grade)
CAS: 50-81-7
Pharmaceutical grade Ascorbic Acid (Vitamin C) is used as an antioxidant stabilizer in oral, parenteral, and topical formulations to prevent oxidative degradation of susceptible APIs and excipients. It scavenges free radicals and reduces dissolved oxygen, protecting formulations during manufacturing and storage. It also finds use as a pH adjuster and as an active ingredient in nutraceutical and vitamin C supplement products.
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Benzyl Alcohol (Pharmaceutical Grade Preservative)
CAS: 100-51-6
Pharmaceutical grade Benzyl Alcohol is an aromatic alcohol used as an antimicrobial preservative and solvent in injectable, topical, and oral formulations. At concentrations of 0.9–2.0%, it is effective against a broad spectrum of microorganisms. It also provides mild local anesthetic properties that reduce injection site pain in parenteral products.
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Calcium Stearate (Pharmaceutical Grade)
CAS: 1592-23-0
Pharmaceutical grade Calcium Stearate is a calcium salt of stearic acid used as a tablet lubricant and glidant. It provides effective lubrication at concentrations of 0.5–2% and is particularly suited for formulations where magnesium ions must be avoided. It has a less pronounced negative effect on tablet hardness and dissolution compared to magnesium stearate.
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Carnauba Wax (Pharmaceutical Grade)
CAS: 8015-86-9
Pharmaceutical grade Carnauba Wax is a natural plant wax obtained from the leaves of the Brazilian Copernicia prunifera palm. In pharmaceutical manufacturing, it is used as a tablet polishing agent to impart a high-gloss finish to sugar-coated and film-coated tablets. Its high melting point (82–86°C), hardness, and water resistance also make it useful as a sustained-release matrix lipid and protective coating component.
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Cellulose Acetate Phthalate (CAP)
CAS: 9004-38-0
Cellulose Acetate Phthalate (CAP) is a widely used enteric coating polymer that remains intact in gastric acid but dissolves above pH 6.0 in the intestine. It provides effective protection of acid-sensitive APIs from gastric degradation and enables targeted drug delivery to the small intestine. It can be applied from organic solvent solutions or aqueous dispersions.
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Citric Acid (Pharmaceutical Grade)
CAS: 77-92-9
Pharmaceutical grade Citric Acid is a tricarboxylic acid used as a pH adjuster, buffering agent, chelating agent, and acidulant in a wide range of oral, parenteral, and topical formulations. Its ability to chelate divalent metal ions makes it particularly effective as a metal-sequestering antioxidant synergist. It is also an essential component of effervescent tablet formulations.
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Colloidal Silicon Dioxide (Aerosil 200)
CAS: 7631-86-9
Colloidal Silicon Dioxide (Aerosil 200) is a fumed amorphous silica with a surface area of approximately 200 m²/g, used as a glidant and adsorbent in pharmaceutical formulations. At low concentrations (0.1–0.5%), it significantly improves powder flow by reducing inter-particle friction. It is also used as a suspending agent and thickener in liquid and semisolid preparations.
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Copovidone VA64 (Kollidon VA64)
CAS: 25086-89-9
Copovidone VA64 is a copolymer of vinylpyrrolidone and vinyl acetate in a 6:4 ratio, known commercially as Kollidon VA64. It combines the excellent binding properties of PVP with the plasticizing effect of PVA, making it ideal for hot melt extrusion (HME) and spray-drying applications for amorphous solid dispersion formation. It is widely used to enhance bioavailability of BCS II and IV drugs.
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Corn Starch (Pharmaceutical Grade)
CAS: 9005-25-8
Pharmaceutical grade Corn Starch is a natural polysaccharide derived from maize, widely used as a disintegrant, binder, and diluent in tablet and capsule formulations. It swells rapidly upon contact with water, promoting tablet disintegration and drug release. It is inexpensive, widely available, and compliant with major pharmacopoeial standards.
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Croscarmellose Sodium (Ac-Di-Sol)
CAS: 74811-65-7
Croscarmellose Sodium is a crosslinked polymer of carboxymethylcellulose sodium used as a superdisintegrant in solid oral dosage forms. It provides rapid and efficient tablet disintegration through a combination of swelling and wicking mechanisms, and is effective at low concentrations (1–5%). Compliant with USP/NF, EP, and JP monographs.
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Crospovidone (PVPP)
CAS: 9003-39-8
Crospovidone (crosslinked polyvinylpyrrolidone, PVPP) is a highly efficient superdisintegrant that functions primarily through a wicking mechanism rather than swelling. It is insoluble in water and organic solvents, making it chemically stable and compatible with a wide range of APIs. It is effective at low concentrations and produces rapid, consistent tablet disintegration.
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Dibasic Calcium Phosphate (DCP)
CAS: 7757-93-9
Dibasic Calcium Phosphate (DCP) is a widely used inorganic diluent and filler for tablets and capsules, valued for its excellent compressibility and high drug loading capacity. It is chemically inert, non-hygroscopic, and compatible with most APIs. Available in both anhydrous and dihydrate forms to suit various formulation requirements.
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Ethylcellulose N10 (EC N10)
CAS: 9004-57-3
Ethylcellulose N10 is a water-insoluble cellulose ether with a 5% toluene/ethanol viscosity of approximately 10 mPa·s, used as a film coating material for sustained-release applications and as a binder in sustained-release matrix tablets. It forms robust, moisture-resistant films that are impermeable to water, enabling precise control of drug diffusion.
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Eudragit E PO (Basic Butylated Methacrylate Copolymer)
CAS: 24938-16-7
Eudragit E PO is a cationic copolymer based on dimethylaminoethyl methacrylate that dissolves below pH 5.0 in gastric fluid, making it a gastro-soluble polymer. It is widely used as a taste-masking and moisture-protective film coating for tablets and pellets. It also finds application as a binder and hot melt extrusion carrier for solubilization of poorly soluble drugs.
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Eudragit L100 (Methacrylic Acid Copolymer Type A)
CAS: 25212-88-8
Eudragit L100 is an anionic copolymer of methacrylic acid and methyl methacrylate used as an enteric coating polymer, dissolving at pH 6.0 and above. It provides reliable protection against gastric acid and enables targeted drug release in the duodenum and jejunum. It is applied from organic solvent or aqueous dispersion coating systems.
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Eudragit RS PO (Ammonio Methacrylate Copolymer Type B)
CAS: 33434-24-1
Eudragit RS PO is a water-insoluble copolymer with low permeability, based on neutral methacrylic esters with a small proportion of quaternary ammonium groups. It swells in contact with water and controls drug release through diffusion, providing pH-independent sustained release. It is commonly used in pellet and matrix tablet formulations for extended drug delivery.
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Ferric Oxide Red (Iron Oxide Red)
CAS: 1309-37-1
Pharmaceutical grade Ferric Oxide Red (Iron Oxide Red, E172) is an inorganic iron oxide pigment used as a colorant in tablet coatings, capsule shells, and pharmaceutical preparations. It provides stable, light-fast red-brown coloration and is insoluble in water, ensuring color consistency throughout the shelf life. It is also used in cosmetics and food products.
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Glycerin (Pharmaceutical Grade)
CAS: 56-81-5
Pharmaceutical grade Glycerin (glycerol) is a trihydric alcohol used extensively as a humectant, solvent, sweetener, and plasticizer in oral, topical, parenteral, and ophthalmic formulations. Its hygroscopic nature, high water miscibility, and low toxicity make it a versatile excipient for liquid and semisolid preparations. It is also used as a suppository base and as a lubricant in capsule fill operations.
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Glyceryl Behenate (Compritol 888 ATO)
CAS: 18641-57-1
Glyceryl Behenate (Compritol 888 ATO) is a mixture of glycerol mono-, di-, and tribehenate used as a lipid matrix former for sustained-release tablets and pellets, and as a lubricant in solid dosage forms. Its high melting point (65–77°C) enables melt granulation and hot melt extrusion processes. It provides pH-independent controlled release by forming a lipid barrier around the drug.
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Hydroxypropyl Cellulose LF (HPC LF)
CAS: 9004-64-2
Hydroxypropyl Cellulose LF is a low-viscosity grade of HPC with a 2% aqueous viscosity of approximately 75–150 mPa·s, primarily used as a binder in tablet and granule formulations. It dissolves in both water and organic solvents and exhibits thermoplastic properties, making it suitable for hot melt extrusion processes in addition to conventional manufacturing.
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Hydroxypropyl Methylcellulose E5 (HPMC E5)
CAS: 9004-65-3
Hydroxypropyl Methylcellulose E5 (HPMC E5) is a low-viscosity grade of HPMC with a 2% aqueous solution viscosity of approximately 5 mPa·s, widely used as a film coating agent, binder, and viscosity modifier. Its excellent film-forming properties and solubility in both water and organic solvents make it suitable for immediate-release coating and tablet binding applications.
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Hydroxypropyl Methylcellulose K4M (HPMC K4M)
CAS: 9004-65-3
HPMC K4M is a high-viscosity, sustained-release grade of hydroxypropyl methylcellulose with a 2% aqueous viscosity of approximately 4000 mPa·s. It forms a robust gel barrier upon hydration, controlling drug diffusion and enabling extended drug release profiles. It is the cornerstone excipient in hydrophilic matrix tablet technology.
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Hypromellose Acetate Succinate (HPMCAS)
CAS: 71138-97-1
Hypromellose Acetate Succinate (HPMCAS) is a cellulose derivative used as an enteric coating polymer and as a carrier in amorphous solid dispersions (ASD) for bioavailability enhancement. It dissolves above pH 5.5 to 6.8 depending on the grade (LF, MF, HF), providing targeted intestinal drug release. It is the most widely used polymer for spray-dried dispersions of poorly soluble drugs.
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Lactose Anhydrous
CAS: 63-42-3
Lactose Anhydrous is the water-free form of lactose, offering lower moisture content and superior flowability for direct compression applications. It is the excipient of choice for moisture-sensitive APIs and high-speed tableting operations. Compliant with USP/NF, EP, and JP pharmacopoeial standards.
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